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Home » AI Agent & Copilot Podcast: Marie Wiese on Real-World AI Adoption, Innovation, and the Human Side of Change
AI and Copilots

AI Agent & Copilot Podcast: Marie Wiese on Real-World AI Adoption, Innovation, and the Human Side of Change

John SiefertBy John SiefertFebruary 2, 20262 Mins Read
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Marie Wiese, CEO of Marketing Copilot and Microsoft MVP, joins John Siefert in this episode of the AI Agent & Copilot Podcast. Wiese highlights the transformational impact of AI on businesses and individuals, underscoring the importance of change management and innovation. She also details a new book release and what the AI Agent & Copilot Summit will provide attendees.

Key Takeaways

  • AI’s progress: Wiese expresses excitement to return to the event after a year to hear real case studies on how people have embraced AI, especially appreciating the human and change management side of this transformational journey. Specifically, she’s eager to learn where organizations have tested, scaled, or faced pushback over the past 12 months, noting that adopting AI is an ongoing, iterative process.
  • Curating the agenda: “I think my number one view of all of the submissions was around innovation,” notes Wiese, who played a role as a Programming Committee Board member, selecting sessions for the 2026 AI Agent & Copilot Summit agenda. In her process, she looked for examples of where organizations have truly innovated with this technology. “I want honest, too. You know, ‘this is what we tried. It didn’t work, but we came back at it, here’s how'”.
  • AI’s impact on women in tech: On Thursday, March 19, Wiese will lead a Fireside Chat around her new book, “You’re on Mute.” The book explores whether AI has actually helped women enter and thrive in the tech industry amid persistent adoption and trust gaps. Through stories from contributors, it examines AI’s impact on leveling the playing field and encourages more women to see AI as a path into tech.
  • Event expectations: The real power of conferences and events comes from being together, notes Wiese. With the lineup of speakers, she believes attendees will gain access to candid insights and meaningful peer connections.

AI Agent & Copilot Summit is an AI-first event to define opportunities, impact, and outcomes with Microsoft Copilot and agents. Building on its 2025 success, the 2026 event takes place March 17-19 in San Diego. Get more details.

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John Siefert

CEO
Cloud Wars, Dynamics Communities

Areas of Expertise
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  • Cloud
  • LinkedIn

John Siefert is the CEO of Dynamics Communities and Cloud Wars, where he leads the strategic direction, business, and community-based focus of the organization by collaborating with colleagues, customers, partners, and friends. Prior to DCI, Siefert has worked in multiple leadership positions, including President roles at Questex and Informa, SVP at UBM, CMO at STYR Labs, and CEO at Virgo, LLC. Siefert’s passion for creating unique content, community, and event-based programming has helped to build some of the largest media brands in the B2B market, serving the business technology and health/nutrition categories. In his personal life, Siefert is a father of two, married to the love of his life, and digs beaches, barbecues, boats, astrophysics, and road-tripping.

  Contact John Siefert ...

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Recent Posts
  • Microsoft Quarterly Report Details Big Customer Wins in Agents, Copilots, and Healthcare
  • AI Agent & Copilot Podcast: Marie Wiese on Real-World AI Adoption, Innovation, and the Human Side of Change
  • Propelled by Strong Q4, SAP CEO Klein Lays Out 5-Point Growth Plan
  • Microsoft Taps Power of AI To Expand Breadth, Depth of Security Investigations
  • Two Female-Led Microsoft Partners Join Forces: TMC Acquires TMG

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